Paroxetine Impurity 55 CAS 112058-89-6 (free base)
| CAS No. | 112058-89-6 (free base) |
| Molecular Formula | C19H22FNO3 |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 367.84 g/mol gives Paroxetine Impurity 55 distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
As a process- or degradation-related impurity, Paroxetine Impurity 55 (CAS 112058-89-6 (free base), C19H22FNO3HCl) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Paroxetine Impurity 55 (C19H22FNO3HCl) contains a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a certified reference material (CRM), Paroxetine Impurity 55 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C19H22FNO3 HCl |
| Molecular Weight | 367.84 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 1 |
Related Paroxetine Standards
- Paroxetine Impurity 62 (CAS 100332-12-5)
- Paroxetine Impurity 43 (CAS 100332-20-5)
- Paroxetine EP Impurity G HCl (CAS 1012886-75-7)
- Paroxetine Impurity 24 (CAS 105812-81-5)
- Paroxetine EP impurity C (CAS 105813-14-7)
- Paroxetine HCl EP Impurity C (CAS 105813-14-7(free base))
- Paroxetine EP Impurity F HCl (CAS 105813-39-6)
- Paroxetine Impurity 47 (CAS 105813-40-9)
Recommended Standards
- Lansoprazole Impurity 42 (CAS CATO-C4X-111342)
- Posaconazole Impurity 131 (CAS CATO-C4X-1208131)
- Valproate impurity 89 (CAS CATO-C4X-116689)
- 2-(Piperidin-3-yl)piperidine (CAS 2467-09-6)
- 5-Bromo-1-t-butyl-6,7-difluorobenzimidazole (CAS 1375069-11-6)
- 2-[(2H-1,3-Benzodioxol-5-yl)amino]-4-chloro-1,3-thiazole-5-carbonitrile (CAS 866156-03-8)
- N-(2,4-Dinitrophenyl)-5-methoxytryptamine (CAS 124035-04-7)
- 2-Ethynylspiro[3.3]heptan-2-ol (CAS 2621398-43-2)
- (Z)-N-(1-Chloro-3-oxo-3-(piperidin-1-yl)-1-(p-tolyl)prop-1-en-2-yl)benzamide (CAS 1323140-63-1)
- Semaglutide impurity 270 (CAS CATO-C4X-2226270)
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